:root {
  --bg: #f5f9ff;
  --text: #152c48;
  --muted: #5a6780;
  --card: #ffffff;
  --line: #d0daf0;
  --accent: #3b74f5;
  --nav-text: #2a4268;
}

* {
  box-sizing: border-box;
}

html {
  scroll-behavior: smooth;
}

body {
  margin: 0;
  font-family: -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, Helvetica, Arial, sans-serif;
  background:
    radial-gradient(ellipse 80% 50% at 50% -10%, #e8f0ff 0%, transparent 55%),
    radial-gradient(circle at 12% 20%, rgba(200, 220, 255, 0.45) 0%, transparent 42%),
    radial-gradient(circle at 88% 30%, rgba(210, 236, 255, 0.4) 0%, transparent 38%),
    var(--bg);
  color: var(--text);
  line-height: 1.65;
}

.container {
  width: min(960px, 92vw);
  margin: 0 auto;
}

.top-nav {
  position: sticky;
  top: 0;
  z-index: 1000;
  backdrop-filter: blur(12px);
  background: rgba(255, 255, 255, 0.78);
  border-bottom: 1px solid rgba(120, 150, 200, 0.22);
  box-shadow: 0 1px 0 rgba(255, 255, 255, 0.8);
}

.top-nav-inner {
  min-height: 56px;
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 0.8rem;
}

.brand {
  color: var(--nav-text);
  font-weight: 700;
  letter-spacing: 0.02em;
  text-decoration: none;
  flex-shrink: 0;
  white-space: nowrap;
}

.brand:hover {
  color: var(--accent);
}

.top-nav-links {
  display: flex;
  align-items: center;
  gap: 0.25rem;
}

.top-nav-links a {
  color: #4a6288;
  text-decoration: none;
  font-size: 0.92rem;
  padding: 0.42rem 0.65rem;
  border-radius: 8px;
}

.top-nav-links a:hover {
  background: rgba(59, 116, 245, 0.1);
  color: var(--accent);
}

.github-btn {
  color: var(--accent);
  text-decoration: none;
  font-size: 0.9rem;
  padding: 0.4rem 0.8rem;
  border-radius: 999px;
  border: 1px solid rgba(59, 116, 245, 0.45);
  background: rgba(255, 255, 255, 0.65);
}

.github-btn:hover {
  background: rgba(59, 116, 245, 0.12);
  border-color: var(--accent);
}

.hero {
  position: relative;
  overflow: hidden;
  background: linear-gradient(
    165deg,
    #f5f8ff 0%,
    #e8f0fc 38%,
    #dce8f8 72%,
    #d0e0f4 100%
  );
  color: var(--text);
  padding: 4.2rem 0 3.5rem;
  text-align: center;
  border-bottom: 1px solid rgba(100, 130, 185, 0.18);
}

.hero::before,
.hero::after {
  content: "";
  position: absolute;
  pointer-events: none;
  background-repeat: no-repeat;
  background-size: contain;
  opacity: 0.11;
}

/* Protein-like ribbon motif (subtle on light hero) */
.hero::before {
  width: 460px;
  height: 460px;
  right: -70px;
  bottom: -120px;
  background-image: url("data:image/svg+xml,%3Csvg xmlns='http://www.w3.org/2000/svg' viewBox='0 0 520 520'%3E%3Cpath d='M52 320c56-81 95-92 142-80 53 13 68 75 116 79 46 4 69-46 120-122' stroke='%236b8fc9' stroke-width='18' fill='none' stroke-linecap='round'/%3E%3Cpath d='M67 246c42-61 70-66 105-58 36 8 48 52 82 55 33 3 52-31 94-89' stroke='%2380a3d4' stroke-width='10' fill='none' stroke-linecap='round'/%3E%3Ccircle cx='115' cy='290' r='10' fill='%2394b4dc'/%3E%3Ccircle cx='214' cy='273' r='9' fill='%2394b4dc'/%3E%3Ccircle cx='302' cy='328' r='8' fill='%2394b4dc'/%3E%3Ccircle cx='390' cy='258' r='8' fill='%2394b4dc'/%3E%3C/svg%3E");
}

/* Antibody-like Y motif */
.hero::after {
  width: 320px;
  height: 320px;
  left: -40px;
  top: 70px;
  opacity: 0.09;
  background-image: url("data:image/svg+xml,%3Csvg xmlns='http://www.w3.org/2000/svg' viewBox='0 0 300 300'%3E%3Cg fill='none' stroke='%236b8fc9' stroke-width='14' stroke-linecap='round' stroke-linejoin='round'%3E%3Cpath d='M150 252V165'/%3E%3Cpath d='M150 165L94 98'/%3E%3Cpath d='M150 165L206 98'/%3E%3Cpath d='M94 98L69 57'/%3E%3Cpath d='M206 98l25-41'/%3E%3C/g%3E%3Ccircle cx='150' cy='164' r='8' fill='%2380a3d4'/%3E%3Ccircle cx='94' cy='98' r='6' fill='%2380a3d4'/%3E%3Ccircle cx='206' cy='98' r='6' fill='%2380a3d4'/%3E%3C/svg%3E");
}

.hero-glow {
  position: absolute;
  pointer-events: none;
  border-radius: 999px;
  filter: blur(10px);
}

.hero-glow-1 {
  width: 420px;
  height: 420px;
  background: rgba(140, 190, 255, 0.35);
  top: -140px;
  left: -120px;
}

.hero-glow-2 {
  width: 520px;
  height: 520px;
  background: rgba(180, 210, 255, 0.4);
  right: -180px;
  top: -180px;
}

.venue {
  margin: 0;
  color: #5a7ab0;
  font-weight: 600;
  letter-spacing: 0.03em;
  text-transform: uppercase;
  font-size: 1rem;
}

h1 {
  margin: 0.8rem 0 1rem;
  font-size: clamp(1.7rem, 3vw, 2.5rem);
  line-height: 1.25;
}

.authors,
.note {
  margin: 0.35rem 0;
}

.authors {
  color: #2c4666;
  font-size: 1rem;
}

.affiliations-inline {
  margin: 0.6rem auto 0;
  max-width: 920px;
  color: #4a6288;
  font-size: 0.9rem;
}

.note {
  color: #5a6f8a;
  font-size: 0.95rem;
}

.corresponding {
  margin: 0.4rem auto 0;
  max-width: 920px;
  color: #4a6288;
  font-size: 0.92rem;
}

.corresponding a {
  color: var(--accent);
  text-decoration: underline;
  text-underline-offset: 2px;
}

.links {
  margin-top: 1.3rem;
  display: flex;
  flex-wrap: wrap;
  gap: 0.6rem;
  justify-content: center;
}

.links a {
  text-decoration: none;
  color: var(--accent);
  border: 1px solid rgba(59, 116, 245, 0.45);
  background: rgba(255, 255, 255, 0.75);
  padding: 0.56rem 1rem;
  border-radius: 999px;
  font-size: 0.95rem;
  transition: transform 0.2s ease, background 0.2s ease, border-color 0.2s ease;
}

.links a:hover {
  background: rgba(59, 116, 245, 0.12);
  border-color: var(--accent);
  transform: translateY(-1px);
}

.page-shell {
  padding: 1.2rem 0 0.5rem;
}

.section {
  padding: 1.3rem 0;
  scroll-margin-top: 76px;
}

.section.alt {
  background: transparent;
  border: none;
}

.content-card {
  background: rgba(255, 255, 255, 0.86);
  backdrop-filter: blur(3px);
  border: 1px solid var(--line);
  border-radius: 16px;
  padding: 1.25rem 1.2rem;
  box-shadow: 0 8px 30px rgba(20, 50, 120, 0.07);
}

h2 {
  margin-top: 0;
  margin-bottom: 0.8rem;
  font-size: 1.6rem;
}

h3 {
  margin-top: 1.6rem;
  margin-bottom: 0.8rem;
}

h4 {
  margin: 0 0 0.7rem;
}

.placeholder-box {
  margin-top: 1rem;
  border: 1px dashed #8ba0c5;
  border-radius: 10px;
  background: var(--card);
  color: var(--muted);
  text-align: center;
  padding: 2rem 1rem;
}

.method-figure {
  margin: 1rem 0 0;
  padding: 0;
  border: 1px solid var(--line);
  border-radius: 12px;
  background: #fff;
  overflow: hidden;
  box-shadow: 0 4px 18px rgba(15, 48, 120, 0.06);
}

.method-figure img {
  width: 100%;
  height: auto;
  display: block;
  vertical-align: middle;
}

.method-figure-caption {
  margin: 0;
  padding: 0.45rem 0.75rem;
  font-size: 0.85rem;
  color: var(--muted);
  text-align: right;
  border-top: 1px solid var(--line);
  background: #fafcff;
}

.method-figure-caption a {
  color: var(--accent);
  text-decoration: none;
}

.method-figure-caption a:hover {
  text-decoration: underline;
}

pre {
  margin: 0;
  background: #111827;
  color: #e5ebf8;
  border-radius: 10px;
  padding: 1rem;
  overflow-x: auto;
}

.footer {
  border-top: 1px solid var(--line);
  padding: 1.1rem 0;
  text-align: center;
  color: var(--muted);
  font-size: 0.95rem;
}

.table-card {
  margin-top: 1rem;
  background: var(--card);
  border: 1px solid var(--line);
  border-radius: 12px;
  padding: 1rem;
  box-shadow: 0 4px 16px rgba(15, 48, 120, 0.06);
}

.table-wrap {
  overflow-x: auto;
}

table {
  width: 100%;
  border-collapse: collapse;
  min-width: 760px;
  font-size: 0.92rem;
}

th,
td {
  border-bottom: 1px solid var(--line);
  padding: 0.5rem 0.55rem;
  text-align: left;
  white-space: nowrap;
}

th {
  background: #f2f7ff;
  font-weight: 600;
}

.highlight-row td {
  background: #e8f1ff;
  font-weight: 600;
}

@media (max-width: 780px) {
  .hero::before {
    width: 300px;
    height: 300px;
    right: -90px;
    bottom: -80px;
    opacity: 0.14;
  }

  .hero::after {
    width: 220px;
    height: 220px;
    left: -70px;
    top: 120px;
    opacity: 0.1;
  }

  .top-nav-inner {
    min-height: 52px;
  }

  .top-nav-links {
    gap: 0.05rem;
  }

  .top-nav-links a {
    font-size: 0.84rem;
    padding: 0.34rem 0.45rem;
  }

  .github-btn {
    font-size: 0.82rem;
    padding: 0.32rem 0.58rem;
  }

  .hero {
    padding: 3.8rem 0 3rem;
  }

  .content-card {
    padding: 1rem 0.9rem;
    border-radius: 12px;
  }

  .authors {
    font-size: 0.94rem;
  }

  .affiliations-inline {
    font-size: 0.84rem;
  }
}